Push for MDMA Therapy to Treat PTSD Despite FDA Concerns

Updated
July 12, 2024
Edited by Ben Smith
Last Updated:
July 18, 2024
A collage-style image of a group of people in a serious discussion around a conference table. They are all wearing exaggerated round glasses, adding a whimsical touch.

Imagine taking a drug that felt like it could ease trauma’s grip. That’s what some lawmakers and advocates are hoping MDMA can do for people with PTSD (Post-Traumatic Stress Disorder).

MDMA, more commonly known as ecstasy, has been shown in studies to help people with PTSD when used in combination with psychotherapy. However, it’s not without its critics and complex issues.

Lawmakers and Advocates Support MDMA

Recently, a group of lawmakers and veterans gathered to show their support for MDMA therapy. These included Rep. Morgan Luttrell, a former Navy SEAL, Rep. Jack Bergman, a retired Marine lieutenant general, and others. They spoke ahead of a big decision from the Food and Drug Administration (FDA).


   "Yes, I have done this, and yes I support this 100% and always will," – Rep. Morgan Luttrell
 

Studies showed a whopping 87% of patients had less severe PTSD symptoms after combining MDMA with therapy. Around 71% of these patients even stopped meeting the criteria for PTSD. That sounds great, right?

FDA Advisory Panel Raises Questions

Well, not everyone is convinced. An FDA advisory panel questioned these studies, saying the research might make the results look better than they are. They pointed out that some participants had used MDMA before, which could make them biased.


   "It seems like there are so many problems with the data -- each one alone might be OK, but when you pile them on top of each other ... there's just a lot of questions I would have about how effective the treatment is," – Melissa Decker Barone from University of Maryland School of Medicine
 

Despite these concerns, the need for new PTSD treatments is urgent. According to the Department of Veterans Affairs, about 17 veterans take their own lives each day. Current treatments include medications like Paxil and Zoloft, but no new PTSD treatments have been approved in over 20 years.

Rep. Bergman was disappointed by the advisory panel’s recommendation against MDMA therapy.


   "Many of us in Congress and especially those who served in uniform were disappointed and frustrated by the recent recommendation," – Rep. Jack Bergman
 

He added that the advisory panel ignored what many veterans were saying in favor of those who oppose the treatment at all costs.

Ongoing and Future Research

Meanwhile, the VA is funding more research on psychedelic treatments, including MDMA and psilocybin (found in magic mushrooms). Medal of Honor recipient and Marine veteran Dakota Meyer also supports the new MDMA therapy.


   "It's not a cure-all solution for PTSD, but it is and can and will significantly improve the quality of life for those affected," – Dakota Meyer
 

Some veterans’ advocacy groups like Healing Breakthrough and Heroic Hearts Project are also backing the effort. They aim to help veterans with PTSD access these new therapies.

The Call to Action

In addition, Bergman, Luttrell, and Correa are cosponsoring a bill. This bill would require the Defense Department to provide grants for research into psychedelic treatments for active-duty service members with PTSD or other conditions.


   "Our message here today is 'FDA, do your job. Take care of our veterans. Save veterans from suicide,'" – Rep. Lou Correa
 

The supporters of MDMA therapy believe that while it may not be a magical cure, it holds significant promise for improving the lives of those affected by PTSD. The fight for this new treatment is far from over, as advocates continue to push for more research and approval.

What’s Next?

With mixed views from both supporters and the FDA advisory panel, the future of MDMA therapy for PTSD is still uncertain. The FDA's decision, expected by August 11, will be a major milestone. Regardless of the outcome, research and discussions about MDMA as a potential treatment for PTSD are likely to continue.

In the end, the goal remains the same: finding effective treatments to help those suffering from the debilitating effects of PTSD and offering them a chance at a better quality of life.

At Psychly, we are committed to upholding the highest standards in our content creation process. We strive to ensure that all statements presented in our articles are supported by reliable, high-quality sources, such as peer-reviewed studies and reputable academic journals.

- The Psychly Team

1. Military.com. (2024). MDMA treatment for post-traumatic stress gets backing from lawmakers, advocates, FDA raises questions. https://www.military.com/daily-news/2024/07/11/mdma-treatment-post-traumatic-stress-gets-backing-lawmakers-advocates-fda-raises-questions.html

2. Mithoefer, M. C., et al. (2019). MDMA-assisted therapy for treatment of chronic posttraumatic stress disorder: a randomized phase 2 controlled trial. Journal of Psychopharmacology, 33(5), 542-553. https://doi.org/10.1177/0269881118821339

3. Jerome, L., et al. (2020). Long-term follow-up outcomes of MDMA-assisted therapy for treatment of PTSD. Journal of Psychopharmacology, 34(1), 38-46. https://doi.org/10.1177/0269881119897616

4. National Institute of Mental Health. (2022). Post-traumatic stress disorder. https://www.nimh.nih.gov/health/topics/post-traumatic-stress-disorder-ptsd/index.shtml

5. Department of Veterans Affairs. (2022). PTSD: National Center for PTSD. https://www.ptsd.va.gov/

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